Altemicidin, a new acaricidal and antitumor substance. II. Structure determination.

نویسندگان

  • A Takahashi
  • D Ikeda
  • H Nakamura
  • H Naganawa
  • S Kurasawa
  • Y Okami
  • T Takeuchi
  • IitakaY
چکیده

The structure of altemicidin, a new acaricidal and antitumor agent, was determined to be (1R,2S,3aR,7aS)-4-carbamoyl-2-hydroxy-6-methyl-1-(sulfamo ylacetamido)-2,3,3a,6, 7,7a-hexahydro-6-azaindene-1-carboxylic acid by a combination of spectroscopic and X-ray crystallographic analysis of its derivatives. Altemicidin is a monoterpene alkaloid.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Altemicidin, a new acaricidal and antitumor substance. I. Taxonomy, fermentation, isolation and physico-chemical and biological properties.

Screening of new insecticidal and acaricidal antibiotics was carried out with reference to anti-brine shrimp activity from actinomycete strains isolated from marine environments. Of 200 actinomycete isolates, one isolate was found to produce a new substance, altemicidin. The strain was isolated from sea mud collected at Gamo, Miyagi Prefecture, Japan, and identified as Streptomyces sioyaensis S...

متن کامل

Synthesis, Characterization, and Crystal Structure Determination of a New Copper(II) Complex: [H2en][Cu(pydc)2].2H2O

The new complex of [H2en][Cu(pydc)2].2H2O (1) (where H2en and pydc are ethylenediammonium and 2,6-pyridinedicarboxylate, respectively) was synthesized by the reaction of a mixture of ethylenediamine (en) and 2,6-pyridinedicarboxylic acid (H2pydc) in a mixture of CH3OH/H2O as solvent. This complex was fully characterized by elemental analysis, IR, UV–Vis spectroscopy as well as single-crystal X-...

متن کامل

A new antitumor substance, BE-18591, produced by a streptomycete. II. Structure determination.

In the course of screening for new antitumor substances, BE-18591 (la) was isolated from cultures of Streptomyces sp. BA18591X). The isolation and physico-chemical properties together with biological activities are reported in the preceding paper. In this paper, the structure elucidation is described. The physico-chemical properties of la were summarized in a previous paper1*. The molecular for...

متن کامل

Binuclear Nickel(II) Complex Containing 6-Methyl-2,2'-bipyridine and Chloride Ligands: Synthesis, Characterization, Thermal Analyses, and Crystal Structure Determination

A new binuclear complex of [{NiCl(6-mbipy)}2(μ-Cl)2] (1) was prepared from the reaction of NiCl2.6H2O and 6-methyl-2,2'-bipyridine (6-mbipy)  in a mixture of methanol and acetonitrile. Suitable crystals of 1 for X-ray diffraction measurement were obtained by slow evaporation of the resulted green solution at room ...

متن کامل

On the Polymorphism of 12-Tungstoborate Heteropolyanion: Structure Determination and Its Functionalization with L-proline

A new structure related to previously reported structure of 12-tungstoborate Keggin-type polyoxometalate, K5[BW12O40], was synthesized and its characterization by single crystal X-ray diffraction shows the polymorph structure. Further attempts have been performed to provide three component compounds based on L-proline, lanthanoid cation and K5[BW12O40] (BW12 (II)) under hydrothermal conditions ...

متن کامل

ذخیره در منابع من

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The Journal of antibiotics

دوره 42 11  شماره 

صفحات  -

تاریخ انتشار 1989